Immunotherapy for Brain Tumor
There has been no change in the management of primary malignant tumors of the brain (Glioblastoma Multiforme and anaplastic astrocytomas – astrocytomas Grades 3 and 4) for 20 years. Immunotherapy results show that radiation therapy can double life expectancy, and chemotherapy may add a few more months to median survival.
The modern use of Gamma Knife radiosurgery has pushed further the survival curve with its high response rate, but still there is no cure for this dreaded disease. Survival may be only 1 year from the time of diagnosis, with fewer than 5% living 5 years. Thus, a new approach had to be undertaken.
Brain tumor cells, being foreign to the body, should be able to be managed by our normal immunologic defenses as they would if a bacterial or viral infection occurred. Furthermore, there should be a “memory” of the foreign pathogen such that if the immune system came in contact with a tumor cell again, it could recognize and destroy it much like a second exposure to chicken pox.
Because of the infiltrative nature of Grade 4 astrocytomas versus the compact nature of Grade 1 astrocytomas, and the presence of their hypothetical “immunosuppressive barrier”, the cure for this tumor must be a biological one such as immunotherapy.
Why doesn’t this occur with primary malignant tumors of the brain? We think that brain tumors have evolved a way to evade our own defenses and produce a “wall” of immunosuppression. The cure for this brain tumor may well lie in the breakdown of this wall, or indeed the overwhelming of this wall with immunotherapy procedures.
If you wish to make a consultation appointment with Dr. Duma, or for further information regarding immunotherapy for brain tumor in Los Angeles, please register on our website. Also, you can reach us at 949-642-6787.
Quality of LifeRequest an appointment
'I was given a couple of months to live. Dr Duma is brilliant.'
'Thanks to Dr. Duma, my brain tumor has completely diminished.'
'He was knowledgeable and patient when addressing my concerns!'
'I am alive today because of Dr. Duma.'
'The standard of care Dr. Duma offers is stellar. '
'You have extended my life, not only in time, but also the quality of life.'
'He is always concerned for my well-being. I trust him with my life!'